Библиографическое описание:
Zinchuk, V. V. The in vitro Effect of a Magnetic Field on the Oxygen-Transport Function and the Gaseous Transmitter System in Blood / V. V. Zinchuk, V. O. Lepeev // Biophysics. – 2018. – Vol. 63, №. 3. – Р. 436-440.
Аннотации:
The effect of an alternating magnetic field with a magnetic flux density of 150 mT on the blood oxygen-transport function was studied. In vitro exposure of blood cells was performed following a 10-day series of in vivo exposure of the rat tail artery in combination with administration of chemical compounds that affect the formation of gaseous transmitters. In vitro exposure to a magnetic field changed the oxygen-trans¬port function of the blood, as observed by a greater decrease in the affinity of hemoglobin for oxygen and an increase in the concentration of gaseous transmitters (nitric oxide and hydrogen sulfide). In animals to which nitroglycerin and sodium hydrosulfide were administered exposure to a magnetic field caused a shift in the oxyhemoglobin dissociation curve to the right; this effect was absent when a nonselective inhibitor of the NO synthase enzyme or an irreversible inhibitor of the cystathionine y-lyase enzyme was added. These results suggest that the magnetic field affects the oxygen-binding properties of the blood by modifying intra-erythrocyte mechanisms that involve gaseous transmitters.
Ключевые слова:
magnetic field, blood, oxygen, gaseous transmitters