Neurotransmitter Systems of Some Brain Regions of Rats Subjected to Chronic Morphine Intoxication

dc.contributor.author	Lelevich, S. V.
dc.contributor.author	Novokshonov, A. A.
dc.date.accessioned	2018-05-21T11:18:11Z
dc.date.available	2018-05-21T11:18:11Z
dc.date.issued	2011-02
dc.identifier.citation	Lelevich, S. V. Neurotransmitter Systems of Some Brain Regions of Rats Subjected to Chronic Morphine Intoxication / S. V. Lelevich, A. A. Novokshonov // Biomedical Chemistry. – 2011. – Vol. 5, № 2. – Р. 175-179.	ru_RU
dc.identifier.uri	http://elib.grsmu.by/handle/files/6905
dc.description	morphine, brain, dopamine, noradrenaline, serotonin, GABA	ru_RU
dc.description.abstract	The content of neurotransmitters and their metabolites was investigated in brain cortex hemispheres, thalamus and brainstem of rats subjected to chronic morphine intoxication (7-21 days). Morphine administration for 7-14 days was accompanied by changes of the catecholamine system functioning, which was the most pronounced in the thalamus and the brainstem. These changes included increased secretion of dopamine and noradrenaline, their decrease in the brain tissue, and an increased content of their metabolites. The changes in serotonin and GABA content were less pronounced and included a decrease of serotonin level and the increase of the GABA content in different periods of opiate administration.	ru_RU
dc.language.iso	ru	ru_RU
dc.title	Neurotransmitter Systems of Some Brain Regions of Rats Subjected to Chronic Morphine Intoxication	ru_RU
dc.type	Article	ru_RU